What is a possible complication of Vena Cava Interruption for recurrent PE?

The correct choice of a possible complication of Vena Cava Interruption for recurrent pulmonary embolism (PE) is night cramps. This can occur as a result of alterations in venous return and overall circulation dynamics after the procedure. When the inferior vena cava is interrupted, there may be changes in blood flow patterns in the lower extremities which can lead to discomfort, nocturnal leg cramps, or muscle spasms at night.

This muscle cramping can be attributed to various factors such as venous stasis, changes in pressure, and ischemia in the lower limbs that might arise from the interruption of normal venous flow. Additionally, the absence of adequate venous drainage can strain muscle metabolism, leading to cramping sensations.

In contrast, diminished cardiac output, edema, and leg ulcers could also be potential complications associated with venous issues, but they are not as directly correlated with the procedure of Vena Cava Interruption specifically in the context of night-time symptoms. These issues may arise in different clinical scenarios but are less specific complications following this particular intervention for recurrent PE.